Chessbase
Three-fold repetition
Chessbase doesn't automatically detect three-fold repetitions. To detect a three-fold repetition (as far as I can tell), identify the move you'd like to claim as being a three-fold, then go to Home, go to the Find Position ribbon, and click In this Game (top right of the Find Position ribbon). If this identifies three positions, this classifies as a three-fold repetition
50-move rule
Chessbase cannot detect the 50-move rule.